Gareth Southgate’s side were sunk by Mikel Oyarzabal’s late winner to leave England heartbroken again and unable to end the long wait for success for the men’s team.
Spain’s young star wingers combined to give them the lead two minutes after the break as Lamine Yamal’s pass opened up space for Nico Williams to beat England keeper Jordan Pickford with a powerful low finish.
Substitute Cole Palmer raised the hopes of another dramatic comeback with a composed left-foot strike after 73 minutes.
However, it wasn’t enough to hold the Spanish side who came roaring back and snatched the win four minutes from time as Oyarzabal slid home Marc Cucurella’s cross to leave England the nearly men once more.